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QD 232

CAS No. 1527467-32-8

QD 232( QD232 )

Catalog No. M12137 CAS No. 1527467-32-8

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    QD 232
  • Note
    Research use only, not for human use.
  • Brief Description
    QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation.
  • Description
    QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation, decreasing pancreatic cancer cell viability and migration; arrests cell cycle progression and induces apoptosis at low micromolar concentrations, shows effectivity in drug-resistant cancer cell lines.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    QD232
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1527467-32-8
  • Formula Weight
    293.282
  • Molecular Formula
    C16H11N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    6-((3-acetylphenyl)amino)quinazoline-5,8-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pathania D, et al. Br J Pharmacol. 2015 Jan;172(1):50-63. 2. Kuang Y, et al. J Med Chem. 2018 Feb 22;61(4):1576-1594.
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