Home - Products - JAK/STAT Signaling - STAT - QD 232

QD 232

CAS No. 1527467-32-8

QD 232( QD232 )

Catalog No. M12137 CAS No. 1527467-32-8

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	873	Get Quote
50MG	1782	Get Quote
100MG	2250	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

QD 232
Note

Research use only, not for human use.
Brief Description

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation.
Description

QD 232 is a novel quinazolinedione-based redox modulator that potently inhibits Src/FAK and STAT3 phosphorylation, decreasing pancreatic cancer cell viability and migration; arrests cell cycle progression and induces apoptosis at low micromolar concentrations, shows effectivity in drug-resistant cancer cell lines.
In Vitro

——
In Vivo

——
Synonyms

QD232
Pathway

JAK/STAT Signaling
Target

STAT
Recptor

STAT
Research Area

——
Indication

——

Chemical Information

CAS Number

1527467-32-8
Formula Weight

293.282
Molecular Formula

C16H11N3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

6-((3-acetylphenyl)amino)quinazoline-5,8-dione

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pathania D, et al. Br J Pharmacol. 2015 Jan;172(1):50-63. 2. Kuang Y, et al. J Med Chem. 2018 Feb 22;61(4):1576-1594.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

FLLL-32

FLLL-32 is a cell-permeable analog of curcumin that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50=5 uM).
NSC 311068

NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5.
GPA 512

The orally bioavailable prodrug of Galiellalactone, a direct inhibitor of STAT3, prevents the transcription of STAT3 regulated genes.

Sign In Join Free